Articles Tagged With:
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Better Diagnostics Equals Fewer Unnecessary Antibiotic Prescriptions
Researchers credit diagnostic stewardship as the top reason for an impressive reduction in needless antibiotic prescriptions.
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Infectious Disease Alert Updates
Screening for Chagas in HIV; It’s Not All About the Cough; Linezolid and Cycloserine in CSF Adequate
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Can Maternal COVID-19 Vaccination Protect Newborns?
In this case control study, 537 case infants younger than 6 months of age who were admitted to the hospital with COVID-19 were compared to 512 control infants who were hospitalized for other reasons; 16% of the case infants and 29% of the control infants had been born to mothers who had been fully vaccinated against COVID-19 during the pregnancy. The effectiveness of maternal vaccination against infant hospitalization for COVID-19 was 52% overall, 80% during the Delta variant period, and 38% during the Omicron variant period. Effectiveness increased when the vaccine was received after 20 weeks of pregnancy.
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Outbreak of a Potentially More Lethal Ebola Virus
A new outbreak of a more lethal Ebola virus is occurring in Uganda with concern about its exportation.
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Antibiotic Prophylaxis Is Not Beneficial for Patients Undergoing Transperineal Prostate Biopsy
A randomized clinical trial found a similar rate of infection between patients given antibiotics for transperineal prostate biopsy compared to those not given antibiotics. It may be possible to omit antibiotics in certain patients undergoing transperineal prostate biopsy.
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COVID-19: Beware Remdesivir Resistance
Hogan and colleagues reported two immunosuppressed renal transplant recipients with persistent SARS-CoV-2 infection in association with the new emergence of mutations in ribonucleic acid (RNA)-dependent RNA polymerase after remdesivir treatment.
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Evidence of Clinical Efficacy of Bebtelovimab in COVID-19
A retrospective study found that bebtelovimab has efficacy similar to that of nirmatrelvir/ritonavir (Paxlovid) in the treatment of high-risk outpatients with recent onset of COVID-19 who have mild to moderate symptoms.
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Oseltamivir for Pediatric Inpatients with Influenza
A large study of children hospitalized with influenza clearly shows that oseltamivir given at or near the time of admission is effective in reducing the duration of hospitalization, reducing the requirement for intensive care, and reducing subsequent readmissions within the week after discharge.
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Concerns and Complications of Measles and Mumps and the Increasing Threat of Monkeypox
Measles and mumps, while clinically dissimilar, share important characteristics that are valuable to discuss in tandem. This review will seek to inform the practitioner about current outbreak concerns regarding measles and mumps, clinical manifestations and complications of each, diagnostic and treatment options, and prevention of further exposures. The emerging threat of monkeypox also is discussed.
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Track the Right Safety Indicators for Best Results
Risk managers can track leading indicators to assess safety improvement efforts, but there is no uniform set of leading indicators for hospitals and health systems. Knowing which indicators to track can make your risk management program more effective.